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Find out more. × Skip main navigation Journal menu Close Drawer Menu Open Drawer Menu Home All Journals Biographical Memoirs Biology Letters Interface Interface Focus Notes and Records Open Biology Philosophical Transactions A Philosophical Transactions B Proceedings A Proceedings B Royal Society Open Science Sign in 0 Cart Search Anywhere This Journal Quick Search anywhere Enter words, phrases, DOI, keywords, authors, etc... Search Go Quick Search in Journals Enter words, phrases, DOI, keywords, authors, etc... Search Go Advanced Search Skip main navigation Journal menu Close Drawer Menu Open Drawer Menu Home Home Content Latest issue All content Subject collections Special collections Perspectives Blog posts Information for Authors Reviewers Readers Institutions About us About the journal Editorial board Author benefits Policies Journal metrics Publication times Open access EMBL partnership Sign up eTOC alerts RSS feeds Newsletters Submit A fast, open access journal publishing high impact biology at the molecular and cellular level Current issue Editor-In-Chief Professor Jonathon Pines FRS Frequency: Monthly ISSN (Online): 2046-2441 Latest articles 2 June 2021 Epidemiological profiles and associated risk factors of SARS-CoV-2 positive patients based on a high-throughput testing facility in India Sumit Malhotra , Manju Rahi , Payal Das , Rini Chaturvedi , Jyoti Chhibber-Goel , Anup Anvikar , Hari Shankar , C. P. Yadav , Jaipal Meena , Shalini Tewari , Sudha V. Gopinath , Reba Chhabra and Amit Sharma 2 June 2021 Brain and testis: more alike than previously thought? Bárbara Matos , Stephen J. Publicover , Luis Filipe C. Castro , Pedro J. Esteves and Margarida Fardilha 2 June 2021 Techniques for RNA extraction from cells cultured in starPEG–heparin hydrogels Anna Jaeschke , Nicholas R. Harvey , Mikhail Tsurkan , Carsten Werner , Lyn R. Griffiths , Larisa M. Haupt and Laura J. Bray 2 June 2021 Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation Chaohui Zhang , Yuxin Li , Jiaheng Cao , Beibei Yu , Kaiyue Zhang , Ke Li , Xinhui Xu , Zhikun Guo , Yinming Liang , Xiao Yang , Zhongzhou Yang , Yunfu Sun , Vesa Kaartinen , Keyue Ding and Jikui Wang See all latest articles Featured articles Open Biology Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells Sianadh Dunn , Olivia Lombardi , Radoslaw Lukoszek and Victoria H. Cowling Basic mechanisms in gene expression are currently being investigated as targets in cancer therapeutics. One such fundamental process is the addition of the cap to pre-mRNA, which recruits mediators of mRNA processing and translation initiation. Maturation ... Read more Open Biology Phosphorylation of Parkin at serine 65 is essential for its activation in vivo Thomas G. McWilliams , Erica Barini , Risto Pohjolan-Pirhonen , Simon P. Brooks , François Singh , Sophie Burel , Kristin Balk , Atul Kumar , Lambert Montava-Garriga , Alan R. Prescott , Sidi Mohamed Hassoun , François Mouton-Liger , Graeme Ball , Rachel Hills , Axel Knebel , Ayse Ulusoy , Donato A. Di Monte , Jevgenia Tamjar , Odetta Antico , Kyle Fears , Laura Smith , Riccardo Brambilla , Eino Palin , Miko Valori , Johanna Eerola-Rautio , Pentti Tienari , Olga Corti , Stephen B. Dunnett , Ian G. Ganley , Anu Suomalainen and Miratul M. K. Muqit Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitochondria ... Read more Open Biology Pigment-Dispersing Factor-expressing neurons convey circadian information in the honey bee brain Katharina Beer , Esther Kolbe , Noa B. Kahana , Nadav Yayon , Ron Weiss , Pamela Menegazzi , Guy Bloch , and Charlotte Helfrich-Förster Pigment-Dispersing Factor (PDF) is an important neuropeptide in the brain circadian network of Drosophila and other insects, but its role in bees in which the circadian clock influences complex behaviour is not well understood. We combined high-resolution ... Read more Open Biology Hidden in plain sight: what remains to be discovered in the eukaryotic proteome? Valerie Wood , Antonia Lock , Midori A. Harris , Kim Rutherford , Jürg Bähler and Stephen G. Oliver The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without ... Read more Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells Sianadh Dunn , Olivia Lombardi , Radoslaw Lukoszek and Victoria H. Cowling Phosphorylation of Parkin at serine 65 is essential for its activation in vivo Thomas G. McWilliams , Erica Barini , Risto Pohjolan-Pirhonen , Simon P. Brooks , François Singh , Sophie Burel , Kristin Balk , Atul Kumar , Lambert Montava-Garriga , Alan R. Prescott , Sidi Mohamed Hassoun , François Mouton-Liger , Graeme Ball , Rachel Hills , Axel Knebel , Ayse Ulusoy , Donato A. Di Monte , Jevgenia Tamjar , Odetta Antico , Kyle Fears , Laura Smith , Riccardo Brambilla , Eino Palin , Miko Valori , Johanna Eerola-Rautio , Pentti Tienari , Olga Corti , Stephen B. Dunnett , Ian G. Ganley , Anu Suomalainen and Miratul M. K. Muqit Pigment-Dispersing Factor-expressing neurons convey circadian information in the honey bee brain Katharina Beer , Esther Kolbe , Noa B. Kahana , Nadav Yayon , Ron Weiss , Pamela Menegazzi , Guy Bloch , and Charlotte Helfrich-Förster Hidden in plain sight: what remains to be discovered in the eukaryotic proteome? Valerie Wood , Antonia Lock , Midori A. Harris , Kim Rutherford , Jürg Bähler and Stephen G. Oliver Aims and scope Open Biology Open Biology is an online journal that welcomes original, high impact research in cell and developmental biology, molecular and structural biology, biochemistry, neuroscience, immunology, microbiology and genetics. Articles submitted to Open Biology benefit from its broad scope and readership and dedicated media promotion and we also aim for a turnaround time of 4 weeks from submission to first decision. Read More Most read Most cited 11 November 2020 Age separation dramatically reduces COVID-19 mortality rate in a computational model of a large population Liron Mizrahi , Huda Adwan Shekhidem and Shani Stern 10 July 2019 The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde? † Diana Vara-Ciruelos , Fiona M. Russell and D. Grahame Hardie 2 June 2021 Brain and testis: more alike than previously thought? Bárbara Matos , Stephen J. Publicover , Luis Filipe C. Castro , Pedro J. Esteves and Margarida Fardilha 1 March 2013 The origin of life: what we know, what we can know and what we will never know Addy Pross and Robert Pascal The Most Read list displays the most accessed articles within a journal for a rolling 12 month period, where “accessed” refers to the HTML and PDF views. See all most read 1 September 2014 Interpreting...